Crystal Palace vs. Liverpool lineups: Predicted starting XI, team news, injury latest with Isak set to replace Ekitike

Football is a game of moments, and sometimes it is not just about the ninety minutes on the pitch, but about the build-up, the fears, the injuries, the decisions, and the drama that surrounds every single clash. That is exactly what is happening right now as Crystal Palace and Liverpool prepare to lock horns in a Premier League battle that is already looking like one of the most talked about fixtures of the week. This is not just another ordinary match; this is a game wrapped in questions, doubts, and high expectations, especially with the breaking news that Alexander Isak is set to replace Hugo Ekitike in Liverpool’s lineup as they prepare for this clash. The story is one of pressure, tactical battles, injury worries, and emotional weight that could shape the outcome of the season for both clubs.
Crystal Palace are not strangers to the fight. They have always been a team that lives on resilience, grit, and the power of Selhurst Park. Every time they step on that pitch, the fans behind them make it feel like a fortress, a place where even giants have fallen before. The story of Palace in recent years has been about survival, about fighting against odds, and about finding those magical nights when underdogs rise to meet giants. This game against Liverpool is another one of those moments. The Eagles know exactly what it means to their fans to take points off one of the biggest clubs in Europe. And when the news dropped that Hugo Ekitike, the man who had been trusted in attack, would not be available, there was anxiety. But then came the twist—the door opening for Alexander Isak.
For Isak, this is more than just a start; it is a statement moment. Signed with huge expectations, he has always been seen as a striker who can hurt defenses with pace, power, and composure in front of goal. Now, with Ekitike absent, it is his time to take the responsibility. Palace fans are dreaming that he can be the one to tear through Liverpool’s defense, and make Selhurst Park roar with joy. This is not just about filling in; this is about taking control of the narrative, about proving to the manager, the fans, and the league that he is the man to lead the line. The tactical decision to bring him in adds a dangerous edge to Palace’s attack, especially with Wilfried Zaha alongside him, ready to run at defenders.
But Liverpool come into this game carrying their own storylines, their own set of challenges and burdens. Under Arne Slot, the Reds are still shaping their new era, still finding their rhythm after years under Jurgen Klopp. The style is changing, the approach is shifting, and the squad is being tested in every single game. Injuries have not made things easier. Luis Díaz has been struggling with fitness, Thiago Alcântara remains a constant concern, and the workload on players like Mohamed Salah and Darwin Núñez continues to grow. Liverpool are a side that lives on intensity, but questions remain—can they keep up that level with key men missing? Can they balance domestic and European commitments with a squad that is already stretched thin? These are the doubts swirling around as they prepare for Palace.
The predicted Liverpool lineup looks strong on paper, but football is not played on paper. Alisson Becker is set to start in goal, a man who has saved Liverpool countless times, but he knows he will need to be at his sharpest because Selhurst Park is not a kind place for goalkeepers under pressure. The defense is likely to be the familiar backline of Trent Alexander-Arnold, Virgil van Dijk, Ibrahima Konaté, and Andrew Robertson. This group has seen both glory and heartbreak together, but they will need to stand tall against the unpredictability of Zaha and the clinical finishing of Isak. Midfield is another area of debate. Fabinho, Jordan Henderson, and Thiago Alcântara are expected to feature, but Thiago’s fitness remains a cloud. If he is not fully ready, the creativity and control he offers will be missed badly. Up front, the familiar trio of Salah, Núñez, and Díaz (if fit enough) is predicted, but there are still whispers that changes could be forced if injuries worsen.
The tactical battle is already being written. Palace will stay compact, absorb pressure, and then look for counter-attacks with Zaha and Isak bursting into spaces left behind Liverpool’s high line. They know Liverpool love to push up, and that means opportunities will come if they can transition quickly. On the other hand, Liverpool will try to suffocate Palace with possession, with pressing, with waves of attack that test the concentration of defenders like Marc Guéhi and Joachim Andersen. This game could swing on fine margins—one mistake, one lapse in focus, one moment of brilliance.
For the fans, the emotions are running wild. Palace supporters are dreaming of another famous night under the lights, of another upset that makes the headlines. Liverpool supporters, meanwhile, are anxious but hopeful. They know that every point matters in the race for the top four, and dropping points here would be costly. Memories of past games at Selhurst Park come flooding back—some painful, like the famous 3-3 draw in 2014 when Liverpool’s title hopes collapsed, and some dominant victories that showed their power. History matters in football, and history will hang over this clash.
But what makes this game even more dramatic are the injuries and absences. Ekitike’s absence has forced Palace’s hand, but it may turn out to be a blessing if Isak shines. For Liverpool, the concerns over Díaz and Thiago could reshape their approach entirely. Salah will be expected to carry the burden again, but how much longer can he do it alone? Núñez is still fighting to convince everyone he can be the consistent number nine Liverpool need, and this is another test for him.
And then there is the emotional weight of the fans themselves. Selhurst Park will be electric, the chants will be deafening, and every Liverpool pass will be pressed with intensity. This is the type of game where nerves crack, where young players can either rise to glory or fall under pressure. It is a test of character as much as it is of tactics.
Form also plays a role. Palace have been inconsistent, but their best performances have come against bigger sides. Liverpool, on the other hand, have been in strong form, dominating possession and scoring goals, but that does not always translate away from home. Head-to-head records favor Liverpool, but Palace have shown before that history means little when belief is strong.
This match is not just about three points; it is about momentum, belief, and narrative. For Palace, a win would mean proving they can compete with the elite and giving their season a spark. For Liverpool, a win would mean keeping pace with rivals, silencing doubts, and showing that despite injuries, they are still a force to be feared.
In the end, this game is shaping up to be one filled with drama. The injury lists, the tactical adjustments, the pressure on strikers, and the energy of the fans will all combine to create a football story that people will talk about long after the final whistle. The spotlight will be on Alexander Isak, stepping in for Hugo Ekitike, and on Mohamed Salah, carrying the weight of Liverpool’s attack yet again. Every pass, every shot, every challenge will matter. This is Premier League football at its purest form—unpredictable, intense, and utterly captivating.
When the teams walk out, when the anthem echoes, and when the whistle blows, all the doubts, all the predictions, all the injury news will fade away, leaving just the raw truth of the battle on the pitch. For Palace and Liverpool, this is not just a game. This is a test of who they are, and who they want to be this season.