Liverpool are getting ready for one of the biggest games of their season, but as the countdown continues, worry and uncertainty still hang heavily over Arne Slot and his squad. On Thursday evening, the Reds travel to North London to face Arsenal, the runaway leaders of the Premier League, in a match that could have huge consequences for the title race, the top four battle, and the confidence of both teams going into the second half of the season. Yet instead of focusing only on tactics, form, and momentum, Liverpool’s preparation has been overshadowed by injury concerns that refuse to go away.
As things stand, Liverpool could be without as many as five first-team players for the clash at the Emirates Stadium. Some absences are already confirmed, while others remain touch-and-go, leaving Slot waiting anxiously for medical updates and last-minute decisions. For a manager still settling into life at Anfield and trying to stamp his identity on the team, this is far from ideal timing. Arsenal are flying, full of confidence, and playing some of the best football in the league. Liverpool, meanwhile, are being forced to juggle form, fatigue, and fitness at the same time.
The biggest concern of all centres around Hugo Ekitike. The French striker has been one of Liverpool’s standout performers this season and currently leads the club’s scoring charts with 11 goals in all competitions. His movement, pace, and ability to stretch defences have given Liverpool a different dimension in attack, especially in the absence of other key forwards. However, Ekitike was a notable absentee in the 2-2 draw away at Fulham on Sunday, a match in which Liverpool showed both their attacking quality and their defensive vulnerabilities.
Ekitike missed that game due to a hamstring problem, and while initial hopes were that it was nothing serious, the fact he could not even be risked from the bench raised immediate alarm bells among supporters. Hamstring injuries are notoriously tricky, and in a season already packed with games, even a minor issue can quickly become a major one if not handled carefully. Slot has been open about the situation but has also tried to strike a hopeful tone when speaking to the media.
According to the Liverpool head coach, the initial belief was that Ekitike was suffering from delayed onset muscle soreness, commonly known as DOMS. This is a relatively common issue for players, especially during busy periods with little recovery time between matches. Slot explained that the club were hoping Ekitike could at least play a part against Fulham, possibly coming off the bench if needed. However, further checks revealed something slightly more concerning, and the decision was made not to take any risks.
Slot made it clear that player welfare had to come first. With so much of the season still to play, rushing Ekitike back too early could have led to a much longer spell on the sidelines. While that decision may prove wise in the long run, it does little to ease the short-term anxiety ahead of a massive clash with Arsenal. Ekitike’s availability would be a huge boost, not just because of his goals, but also because of what is happening elsewhere in Liverpool’s attack.
Alexander Isak, who was expected to play a major role for Liverpool this season, is already ruled out for several months. The Swedish forward is recovering from surgery on an ankle injury that was both painful and dramatic. The incident occurred before Christmas during Liverpool’s 2-1 away win, when Isak was caught by Tottenham defender Micky van de Ven while scoring the opening goal. The challenge resulted in a fractured fibula, turning what should have been a moment of celebration into the beginning of a long road to recovery.
Isak’s absence has forced Slot to reshuffle his attacking options and place even more responsibility on players like Ekitike. Without Isak, Liverpool lose a powerful, intelligent forward who can hold up play, link midfield to attack, and score crucial goals in tight matches. That makes the situation around Ekitike even more critical. If he is not fit to start against Arsenal, Liverpool could be left severely short in the final third against one of the strongest defences in the league.
There is slightly better news when it comes to Florian Wirtz. The German playmaker has been managing hamstring soreness of his own over the busy Christmas period, but he showed his importance once again by featuring and scoring against Fulham. Wirtz’s ability to find space between the lines, pick out clever passes, and contribute goals from midfield has quickly made him one of Liverpool’s most important players. His presence against Arsenal could be vital, especially if the Reds are missing key attackers ahead of him.
Even so, Wirtz is not completely free from concern. Hamstring problems can linger, and playing through discomfort always carries some risk. Slot and his medical team will need to carefully assess whether Wirtz can start again at full intensity or whether his workload needs to be managed. Against Arsenal, there is little room for half-measures. Every player on the pitch will need to be close to 100 percent to cope with the pace and intensity that Mikel Arteta’s side bring.
Another guaranteed absence is Mohamed Salah. The Egyptian superstar remains away on international duty at the Africa Cup of Nations, where Egypt have just progressed to the quarter-finals. While Liverpool supporters will be proud to see Salah representing his country and performing on a big stage, his absence is always felt deeply at Anfield. Salah is not just Liverpool’s most famous player; he is often their difference-maker in the biggest games.
Without Salah, Liverpool lose goals, creativity, experience, and a constant threat that opposition defences must always account for. His runs in behind, his ability to score from tight angles, and his calmness under pressure are all qualities that are almost impossible to replace like-for-like. Against a well-organised Arsenal side, not having Salah available is a major blow, especially when combined with the injury issues elsewhere in the squad.
Defensively, Liverpool are also dealing with long-term problems. Teenage centre-back Giovanni Leoni is ruled out for the rest of the season after undergoing ACL surgery in September. While Leoni may not yet be a regular starter, his absence still affects the squad’s depth and flexibility. Young players like him often provide valuable cover during congested periods, and losing him removes one more option from Slot’s already limited defensive resources.
The cumulative effect of these absences is significant. Potentially missing five players against the league leaders is not something any manager would welcome, especially in such a high-stakes fixture. Arsenal are strong, settled, and confident, while Liverpool are still adapting to a new manager and a new way of playing. Injuries and international call-ups have disrupted rhythm and continuity, making it harder to build momentum.
From Arsenal’s point of view, this situation may look like an opportunity. They know Liverpool will still be dangerous, even with players missing, but they will also be aware that this could be a chance to press home their advantage at the top of the table. For Liverpool, the challenge is clear. They must find a way to compete, regardless of who is available, and show that they can still rise to the occasion when circumstances are against them.
Arne Slot’s role in all of this is crucial. The Dutch coach has already shown calmness and clarity in his communication, even when faced with difficult situations. He has refused to panic publicly and has instead focused on preparing the players he does have at his disposal. That approach will be tested again as the Arsenal game approaches and final fitness decisions are made.
Slot knows that games like this can define a season. A positive result at the Emirates, even with a weakened squad, could provide a huge psychological boost and send a message that Liverpool remain serious contenders. On the other hand, a heavy defeat could raise uncomfortable questions about depth, resilience, and the club’s ability to cope with adversity.
Much will depend on the final call regarding Ekitike. If the striker is passed fit, even if only to play a limited role, it would lift the mood around the squad and among the fans. His presence alone forces defenders to think differently and opens up space for others. If he is ruled out, Liverpool will need to find goals from elsewhere and rely on teamwork, discipline, and moments of inspiration.
The midfield battle will also be key. With Wirtz likely to feature, Liverpool will look to control possession and disrupt Arsenal’s rhythm. That is easier said than done against a side that presses aggressively and moves the ball quickly. Every misplaced pass could be punished, and every lapse in concentration could prove costly.
Defensively, Liverpool will need to be at their absolute best. Arsenal’s attacking players are in form, confident, and ruthless when given space. Without full strength at the back and with limited options from the bench, concentration and organisation will be vital. Small mistakes that might go unpunished against other teams are unlikely to be forgiven by Arsenal.
For the fans, this match comes with mixed emotions. There is excitement about facing the league leaders and the possibility of a statement performance. At the same time, there is anxiety about injuries, missing stars, and the feeling that Liverpool are not quite going into the game on equal footing. Supporters will be hoping for positive news from the medical room right up until kick-off.
As Thursday evening approaches, the waiting continues. Slot and his staff will monitor training sessions, review medical reports, and make tough decisions. Some players may push themselves to be available, knowing how important the game is. Others may be held back to protect them for the long term. It is a delicate balance between ambition and caution.
One thing is certain. Liverpool’s trip to Arsenal will be a test of character as much as quality. Injuries, absences, and setbacks are part of football, but how a team responds to them often defines its identity. Whether with a full squad or a patched-up lineup, Liverpool will need courage, belief, and togetherness if they are to come away from the Emirates with something to show for their efforts.
In many ways, this match sums up the challenge facing Arne Slot in his first season. He is trying to build something new while dealing with the unpredictable realities of elite football. Injuries do not wait for the “right” moment, and international tournaments do not pause for club ambitions. Slot’s task is to adapt, motivate, and find solutions, even when options are limited.
As fans count down the hours and refresh their feeds for team news, the uncertainty remains. Will Ekitike be fit? Can Wirtz go again? How will Liverpool cope without Salah and Isak? The answers will soon be revealed, but whatever happens, this trip to Arsenal promises drama, tension, and a true test of Liverpool’s resolve
